Fem-Shepard from Mass Effect. Sorry John, but she has a better voice actor and for me at least, it feels more like I'm in the game playing as the female Shepard.

Raiden from Mortal Kombat (Who-da-thunk)

Rose from Legend of Dragoon (minus the fart spell)

Cecil from Final Fantasy III if you played it when it was first release in the US on SuperNES or Final Fantasy IV if your gonna get technical.

Not sure if he counts since he was not playable but Sandal from Dragon Age: Origins.

Nightwolf (Mortal Kombat)
Ermac (Mortal Kombat)
Sonic (Sonic)
Knuckles (Sonic)
Yoshi (Mario)
Nathan Drake (Uncharted)
Samus Aran (Metriod) - Can't believe there isn't more love for her?!

Kung Lao and Mileena are tied at the top of my list. They were always fun as hell for me to play as.

Scorpion (MK)
John Marston (RDR)
Allistair (Dragon Age Origins)

Scorpion

closely followed by.....

Kazuya (Tekken)

Jill Valentine-Resident Evil

Chris Redfield-Resident Evil

Albert Wesker -Resident Evil

Excella Gionne-Resident Evil 5

Liu Bei-Dynasty Warriors

Zhuge Liang-Dynasty Warriors

Lara Croft-Tomb Raider

Akuma FTW.

Mr. Grimm(Twisted Metal:Black)
Mr. Grimm(Twisted Metal 1, 2, and Head On)
Mr. Grimm(Twisted Metal PS3)
Sweet Tooth(Twisted Metal 1, 2, Black, Head On, and PS3)
Preacher(Twisted Metal PS3)
Sub-Zero(MK series)
Scorpion(MK series)
Liu Kang(MK Series
Noob Saibot(MK series)
Crash Bandicoot(Crash Series)
Spyro the Dragon(Spyro series)
Jet Bradley(Tron 2.0)

MKD: Dark Raiden
GTA 4: Niko Belic-he's cold bloooded i like that lol
Nintendo 64 smash bro's: Zelda

My Top 20 in Complete order. First to last.

#1.) Ryu Hayabusa


2.) C.J.


3.) Akuma


4.) Shao Kahn


5.) Wario


6.) Shadow the Hedgehog


7.) Master Chief


8.) Bryan Fury


9.) Vergil


10.) Magneto(Marvel-vs-Capcom:2)


11.) Blackheart(Marvel-vs-Capcom:2)


12.) War-Machine(Marvel-vs-Capcom:2)


13.) Shinnok


14.) Jax



15.) Jade


16.) Noob-Smoke(MK:Deception)


17.) Mileena


18.) Baraka


19.) Agent-47


20.) Snake

Turok

Sub-Zero MK2 -3 -4-

Soap Mactavish COD4 COD MW2

Stryker MK

Kabal MK

Johnny Cage MK

Smoke MK3 (NINJA)

Cyrax MK

Sektor MK

Stryker (Mortal Kombat)
Scorpion (Mortal Kombat)
Cyrax (Mortal Kombat)
Lara Croft (Tomb Raider)
Hammerhead (Twisted Metal)
Sweet Tooth (Twisted Metal)
Spectre (Twisted Metal)
Crash Bandicoot (Crash Bandicoot)
Spyro (Spyro The Dragon)
Rayman (Rayman)
Viewtiful Joe (Viewtiful Joe)
CJ (GTA San Andreas)
Eddy Gordo (Tekken)
Marshall Law (Tekken)
Bryan Fury (Tekken)
Paul Phoenix (Tekken)
Gabe Logan (Syphon Filter)

mk;

Zub, raiden, jade, kenshi, kira, noob saibot&smoke.

street fighter:

Blanka, mr bison, zangif, ryu.

Killer Instinct:

Orchid, sabrewulf,spinal, fulgore, thunder, glacius. cinder.

My all time favorite... Mario.

But I love all the Mortal Kombat characters as well. Well, maybe not ALL of them.

FOREVER SCORPION AND NOBONAGA ODA