Yes, yes.

yup , lol would be wierd since its not for gamecube, wonder how that would be for mka

Yes, actually, you can.

MK:A for the Wii has actually 3-4 styles of playing, it includes the GC controller, the Virtual Console Controller, and the Wii-mote with nun-chuk attachment or just the Wii-mote tilted Horizontally, to play like a regular controller.

And it does kind of feel weird playing the game with the GC controller, haha.

Yep, that's one of good things about Nintendo unlike the other two consoles of options you have.You have 3 options of different controllers, Wii remote, Classic controller or the GC(Gamecube) controller.

Enjoy!

Gamecube Controller= Hella Pwnage
Classic Controller= Less Pwnage
Wii Controller= Takes some getting used to. I use GC usually.
Wii Controller Sideways= Only useable for motor kombat.