Here's a fun bit of trivia, enjoy!

*Edit, forgot Peter Weller, added specific chars/eps, changed title to not imply leads.

Mortal Kombat 1995 Film
Cary-Hiroyuki Tagawa - Shang Tsung (Played Court Bailiff in Pilot TNG episode "Encounter at Farpoint")
Jeff Imada - A Double for Chris Casamassa/Scorpion (Stunt Double for George Takei in ST: VI)
Loyd Kino - Liu Kang's Grandfather (Played Wu in TOS episode "The Omega Glory")
Frank Welker - Shao Kahn voice (Voiced Spock's screams in ST: III, an alien in VOY episode "Nothing Human", and voicework in a few games)

Mortal Kombat Annihilation
Carolyn Seymour - Elder God of Water (Played Romulan Sub-Commander Taris in TNG episode "Contagion", Malcorian Astronomer Mirasta Yale in TNG "First Contact", Romulan Commander Toreth in TNG "Face of the Enemy", and Holodeck char Mrs. Templeton in VOY "Cathexis" & "Persistence of Vision")
Reiner Schone - Shinnok (Played Esoqq in TNG episode "Allegiance")
Brian Thompson - Shao Kahn (Played Klingon Lieutenant Klag in TNG episodes "A Matter Of Honor" & "Shades of Gray", Dosi named Inglatu in DS9 "Rules of Acquisition", Klingon Helm Officer in Generations, Jem'Hadar Toman'torax in DS9 "To the Death", and Romulan Admiral Valdore in the Romulan arc of ENT)
Musetta Vander - Sindel (Played Derran Tal in VOY episode "The Disease")
Dana Hee - Mileena (Stunt Double for Jeri Ryan/7of9)
Marjean Holden - Sheeva (Played Crewman Stolzoff in DS9 episode "Empok Nor")

Mortal Kombat Defenders Of The Realm
Brock Peters - Ramath (Admiral Cartwright in Star Trek IV & VI, Ben Sisko's father in DS9)

Mortal Kombat Legacy
Jeri Ryan - Sonya (Played Seven of Nine on VOY & PIC)

Mortal Kombat 2021 Film
Joe Taslim - Sub-Zero (Played Manas in Star Trek Beyond

Mortal Kombat 11
Peter Weller - Robocop (Played an anti-alien terrorist in the "Terra Prime" arc of ENT, and Admiral Alexander Marcus in Star Trek Into Darkness)

Ka-Tra