I liked a lot of the female characters in the Mk universe over the years,but also hated them in ways.....here's a small rundown w/ my opinions
Sonya=Always had a place for her because she was the very first and only female fighter in MK 1.....she had no cons for mk 1 at all,likely the best choice to use in that game......I had a problem w/ her in DA though,the mk team just changed her for the worse,and took her leg move way:(
Mileena=she always kicked ass.....the sais were both useful in short and long range attacks,her dissapear move was extremely useful,along w/ her fly move.....seeing her creepy face and teeth for the first time in mk2,especially her fatalities,really won me over
Kitana=kinda boring,but her fans could be used well at times
SheevA=kickass......the first time we got to play as,well,basically Goro w/ boobs lol......killer moves and high damage in mk3
Jade=so amazing in umk3....probably the most challenging female to fight against....
Sindel=I'm into horror movies,always have been,but Sindel is more B-movie horror style in design,and I usually laugh at shit like that,but sindel in mk3 was phenomenal.....her hair whip was perfect long range,her hover move confused the opponent plenty of times,and her scream fatality made my jaw drop basically.....she will kick ass in deception undoubtedly!
Li mei=perfect in Da and very powerful/quick.....she will kick so much ass in Deception!

The "super unlockable" ones of course.

Definately Stryker.
Wait.... in Deception? Damn... Do they have to be playable?
Seriously, I would have to go with Sindel. Second would be Mileena. Third Kira.

Jade, she is the most cunning..but tanya looks good too Can't wait for deception!! Mileena too, cuz she has sexy teeth, lol jk. All of you will feel my jade and tanya might on x box live!!

Mileena !! (My long-time personal favorite) but also the rest of my top 5: Li Mei, Tanya, Jade and Kitana.